Medical News Today: What to know about paranoid personality disorder

Researchers have only recently begun to study PPD, so doctors know little about treating the condition.

No clinical trials are available for PPD because it is not currently a high priority for clinicians, and there is a lack of volunteer participants.

However, doctors may sometimes consider the following treatment options for people with PPD.


The Food and Drug Administration (FDA) have not yet approved any drug treatments for PPD.

Some people have suggested treating PPD with the same drugs that healthcare professionals use to treat borderline personality disorder (BPD). The premise for this is that the two conditions share similar diagnostic features, such as hostility and aggression toward others.

Although the FDA have not approved any drugs for BPD either, healthcare professionals may prescribe the following medications to reduce aggression:

However, a 2017 review noted that the effects of these drugs were too small to benefit the recipient significantly.


Similar to drug therapy, doctors do not know much about the effectiveness of psychotherapy for PPD.

However, many psychiatrists believe that cognitive behavioral therapy may help alleviate PPD symptoms, and some case studies support its use.

The overall aim of therapy is to:

  • encourage the person to become more trusting of others
  • stop the person from questioning the loyalty of family and close friends
  • prevent the person from perceiving benign comments as threats
  • stop the person from reacting to perceived insults with anger and hostility
  • encourage the person to become more forgiving of others

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